Speakers:Karel Berka, Palacký University Olomouc, ELIXIR CZMarian Novotný, Charles University, ELIXIR CZAn algorithm AlphaFold was called a scientific breakthrough of the year 2021 by the Science journal the AlphaFold algorithm predicted the 3D structures of proteins from the sequence better than its competitors in the CATH competition in quality indistinguishable from the experimental structure. Since late 2020, AlphaFold has been used to predict 3D structures in a variety of scenarios, including those for which it has not been trained at all. A database of AlphaFold models was created for common use in July 2021, and other tools have been adopted to a new reality of having a powerful tool to predict 3D structure from literally any protein sequence. We are slowly beginning to answer the following questions: How does AlphaFold actually work? How difficult is it to run AlphaFold with my data? How to interpret the AlphaFold models? What tasks are still difficult for AlphaFold? Would we still need an experimental determination of protein structure? In our lecture, we will try to address these questions as much as possible, based on our practical experience with protein structure models.The lecture will take place online.
AlphaFold, an artificial intelligence system which can accurately predict 3D models of protein structures. Created by DeepMind, AlphaFold has the potential to accelerate research in every field of biology. Researchers worldwide justly call it a revolutio
projít na článekIt is with great sadness that we announce the passing of a distinguished figure of Czech science and structural biology, Jaroslav Koča. ELIXIR CZ lost not only its chairman of the Board, but a great colleague.Jaroslav Koča taught at universities in the US
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projít na článekWe cordially invite you to discuss science in-person again. National infrastructure for biological data, ELIXIR CZ, organizes a face-to-face scientific meeting. Join us with an update on your scientific progress in genomics, chemical biology, structural b
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